Mitchell, who was diagnosed with leukaemia in April, defied illness to complete the distance in a time of 24.69 seconds to lower her previous mark in the discipline.

Her time was enough for third place in the event, with Alexa Halko and Kerri Morgan clocking times of 18.79 and 20.21 in their respective classifications.

“This was my first track race at Trials and it was an amazing feeling," said Mitchell.

"I had to overcome a lot this year and that makes it more special.

“I was diagnosed with leukemia in April so to even be here competing with chemotherapy and everything else that is going on makes it really meaningful.

“I’m just honoured to have a chance to make the team, go to Rio and represent USA and everyone fighting with any kind of disability, cancer or whatever the obstacles may be.”

Tatyana McFadden overcame her sister Hannah in the women’s T54 100m, as the triple gold medallist from the London 2012 Paralympic Games recorded a time of 16.09 to earn the victory in the sprint event.

Hannah crossed the line in 16.91 to finish as the runner-up, with Cheri Madsen completing the podium places in 17.47.

Roderick Townsend starred throughout the duration of the second day of the trials, as he first won the men’s T42/43/44/45 long jump by achieving a distance of 7.08 metres.

He was then able to win the 100m T45/46/47 event in a time of 11.22, before the world champion high jumper returned the field events to achieve a winning jump of 2.06m.

David Brown eased to a victory in the men’s T11 100m, alongside his guide Jerome Avery, as the world record holder finished in 11.16.

Lex Gillette ended as runner-up in 11.82, with Tanner Gers finishing on the podium in a time of 12.67.