Daniil Medvedev of Russia is searching for his maiden Grand Slam title, having lost the 2019 US Open final ©Getty Images

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Canadian Félix Auger-Aliassime smashed 12 aces past Bernabe Zapata Miralles in his second round tie ©Getty Images
Canadian Félix Auger-Aliassime smashed 12 aces past Bernabe Zapata Miralles in his second round tie ©Getty Images
Casper Ruud was the biggest casualty of the round as he fell in four sets to Dutchman Botic van der Zandschulp ©Getty Images
Casper Ruud was the biggest casualty of the round as he fell in four sets to Dutchman Botic van der Zandschulp ©Getty Images
Roberto Bautista Agut took a big scalp in Nick Kyrgios before beating Emil Ruusuvuori in the second round ©Getty Images
Roberto Bautista Agut took a big scalp in Nick Kyrgios before beating Emil Ruusuvuori in the second round ©Getty Images
Dan Evans is Britain's last remaining men's player following Cameron Norrie and Andy Murray's eliminations ©Getty Images
Dan Evans is Britain's last remaining men's player following Cameron Norrie and Andy Murray's eliminations ©Getty Images
Second seed Aryna Sabalenka is expected to surpass her previous US Open best when she reached the fourth round ©Getty Images
Second seed Aryna Sabalenka is expected to surpass her previous US Open best when she reached the fourth round ©Getty Images
Elina Svitolina won 91 per cent of points from her first serve against Rebeka Masarova of Spain ©Getty Images
Elina Svitolina won 91 per cent of points from her first serve against Rebeka Masarova of Spain ©Getty Images
Naomi Osaka, one of the tournament favourites, has already won the US Open twice, in 2018 and 2020 ©Getty Images
Naomi Osaka, one of the tournament favourites, has already won the US Open twice, in 2018 and 2020 ©Getty Images